Raw vector
CVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:U/C:H/I:H/A:HSummary
CVE-2025-54307 is a high-severity Path Traversal (CWE-22) vulnerability in Thermofisher Torrent Suite Software. Its CVSS base score is 8.8 (High).
Operationally, exploitation aligns with the MITRE ATT&CK technique Exploit Public-Facing Application (T1190); ranked in the top 49% of CVEs by exploit likelihood; it is not currently listed in the CISA KEV catalog.
The strongest mitigations our analysis identified map to AC-3 (Access Enforcement) and SI-10 (Information Input Validation) — see the control section below for these in your framework.
Deeper analysis AI-assisted summary
Synthesised by an AI model from the NVD description and linked references — a reading aid, not an authoritative source.
CVE-2025-54307, published on 2025-12-04, is a path traversal vulnerability (CWE-22) affecting the Thermo Fisher Torrent Suite Django application version 5.18.1, with a CVSS v3.1 base score of 8.8 (AV:N/AC:L/PR:L/UI:N/S:U/C:H/I:H/A:H). The vulnerability resides in the /configure/plugins/plugin/upload/zip/ and /configure/newupdates/offline/bundle/upload/ endpoints, which allow low-privilege users to upload ZIP files to the server. The plupload_file_upload function constructs the destination file path using either the unsanitized "name" parameter or the uploaded filename; the file extension is extracted by splitting the filename, and a format string is used to build the final path, enabling directory traversal.
An authenticated attacker with low privileges and network connectivity to the server can exploit this issue to write arbitrary files outside the intended directory. By overwriting an executable file such as pdflatex, which is invoked via subprocess.Popen in the write_report_pdf function during requests to /report/latex/(\d+).pdf endpoints, the attacker can achieve remote code execution on the server.
The provided references link to Thermo Fisher documentation, including the Torrent Suite 5.18 user guide (MAN0026163), a product guide for Ion OneTouch 2 and Torrent Suite Software, and the Ion Torrent Suite Software product page, but they do not detail specific advisories, patches, or mitigation steps for this vulnerability.
OWASP Top 10 for Web (2025)
EU & UK References
- 🇪🇺 ENISA EUVD: EUVD-2025-201174
Vulnerability Data
An issue was discovered in the Thermo Fisher Torrent Suite Django application 5.18.1. The /configure/plugins/plugin/upload/zip/ and /configure/newupdates/offline/bundle/upload/ endpoints allow low-privilege users to upload ZIP files to the server. The plupload_file_upload function handles these file uploads and constructs the destination file…
more
path by using either the name parameter or the uploaded filename, neither of which is properly sanitized. The file extension is extracted by splitting the filename, and a format string is used to construct the final file path, leaving the destination path vulnerable to path traversal. An authenticated attacker with network connectivity can write arbitrary files to the server, enabling remote code execution after overwriting an executable file. An example is the pdflatex executable, which is executed through subprocess.Popen in the write_report_pdf function after requests to a /report/latex/(\d+).pdf endpoint.
- CWE(s)
Related Threats
MITRE ATT&CK Enterprise Techniques
CVEs Like This One
Affected Assets
Mitigating Controls
Control response
—
—
—
V5.3.2
Mitigating Controls (NIST 800-53 r5) AI
Enforces the intended directory access authorizations that path traversal would otherwise bypass.
Input validation directly neutralizes special path elements before pathname construction occurs.
Least privilege reduces the impact of any unauthorized file access obtained via traversal.
Mitigating Controls (NIST CSF 2.0) AI
Derived directly from the weakness types (CWEs) cited in the NVD entry via our AI-authored CWE→CSF cross-walk (authority under review) — links open the control.
Patching/maintenance can remediate known path-traversal flaws in deployed software (partial prevention of exploitability) but does nothing to stop the coding defect from being introduced in the first place.
PR.AA-05 defines and reviews access policies but does not address code-level pathname neutralization, so neither direction prevents CWE-22.
Mitigating Controls (ISO/IEC 27001:2022 Annex A) AI
Derived directly from the weakness types (CWEs) cited in the NVD entry via our AI-authored CWE→ISO cross-walk (authority under review) — links open the control.
Security testing in development catches path traversal via static/dynamic analysis.
Secure SDLC mandates input validation and path sanitization that directly prevent path traversal.
Application security requirements include rules for safe file handling and canonicalization.
Secure architecture principles require least-privilege file access and directory isolation.
Secure coding standards explicitly forbid unsafe path construction and mandate safe APIs.
Information access restriction limits which files an application may read or write.