Raw vector
CVSS:4.0/AV:L/AC:L/AT:N/PR:L/UI:N/VC:H/VI:H/VA:H/SC:N/SI:N/SA:N/E:X/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:XCVSS and EPSS are reproduced from their sources (NVD, FIRST EPSS). Risk Priority is our own derived reading, not an NVD score.
Summary
CVE-2026-100841 is a high-severity Deserialization of Untrusted Data (CWE-502) vulnerability in Project-Monai Monai. Its CVSS base score is 8.5 (High).
Operationally, exploitation aligns with the MITRE ATT&CK technique Exploitation for Client Execution (T1203); ranked at the 2th percentile by exploit likelihood (below the median); it is not currently listed in the CISA KEV catalog; a public proof-of-concept is referenced.
The strongest mitigations our analysis identified map to SA-11 (Developer Testing and Evaluation) and SA-8 (Security and Privacy Engineering Principles) — see the control section below for these in your framework.
OWASP Top 10 for Web (2025)
EU & UK References
- 🇪🇺 ENISA EUVD: EUVD-2026-87847
Vulnerability Data
In MONAI 1.6.0, PersistentDataset (monai/data/dataset.py) explicitly rejects the combination track_meta=True with weights_only=True, forcing users who cache MetaTensors (the default tensor type in MONAI >= 1.0) to run torch.load(hashfile, weights_only=False). Related cache helpers in monai/data/utils.py also call pickle.loads on cached content…
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and derive cache keys with hashlib.md5. As a result, a local user with write access to a shared or world-writable cache_dir (e.g. /tmp/monai_cache, HPC scratch, ~/.cache/monai) can place a malicious pickle file that is deserialized the next time another user's MONAI pipeline reads the cache, resulting in arbitrary code execution in that user's context. All released versions of the monai pip package are affected; no patched version is available as of the advisory.
- CWE(s)
Related Threats
MITRE ATT&CK Enterprise Techniques
CVEs Like This One
Affected Assets
Mitigating Controls
Mitigating Controls (NIST 800-53 r5) AI
Developer testing and evaluation can uncover deserialization flaws before deployment.
Engineering principles such as safe deserialization and input sanitization structurally prevent the weakness from being introduced.
Input validation directly stops deserialization of untrusted data by ensuring inputs are valid before processing.
Integrity verification tools can detect malformed or tampered serialized data after the fact.
Mitigating Controls (NIST CSF 2.0) AI
Derived directly from the weakness types (CWEs) cited in the NVD entry via our AI-authored CWE→CSF cross-walk (authority under review) — links open the control.
PR.PS-02 addresses only post-deployment updates/patching and cannot prevent introduction of unsafe deserialization code, yet it can remediate some instances when the flaw exists in outdated libraries or components.
Mitigating Controls (ISO/IEC 27001:2022 Annex A) AI
Derived directly from the weakness types (CWEs) cited in the NVD entry via our AI-authored CWE→ISO cross-walk (authority under review) — links open the control.