Cyber Resilience

CVE-2026-100844

Command Injection in Project-Monai Monai ≤ 1.6.0

Published
27 September 2026
Modified
30 September 2026
Patch / advisory
CVSS Score v4 8.6
Click a component to see what it means
Raw vectorCVSS:4.0/AV:L/AC:L/AT:N/PR:N/UI:N/VC:H/VI:H/VA:H/SC:N/SI:N/SA:N/E:X/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X
EPSS Score 0.0077 54th percentile
Risk Priority 38 floored blend · peak EPSS

CVSS and EPSS are reproduced from their sources (NVD, FIRST EPSS). Risk Priority is our own derived reading, not an NVD score.

Summary

CVE-2026-100844 is a high-severity OS Command Injection (CWE-78) vulnerability in Project-Monai Monai. Its CVSS base score is 8.6 (High).

Operationally, exploitation aligns with the MITRE ATT&CK technique Command and Scripting Interpreter (T1059); ranked in the top 46% of CVEs by exploit likelihood; it is not currently listed in the CISA KEV catalog; a public proof-of-concept is referenced.

The strongest mitigations our analysis identified map to AC-6 (Least Privilege) and CM-7 (Least Functionality) — see the control section below for these in your framework.

OWASP Top 10 for Web (2025)

EU & UK References

Vulnerability Data

MONAI before 1.6.0 is vulnerable to OS command injection in the nnUNetV2Runner component (monai.apps.nnunet.nnunetv2_runner). User-controlled values taken from the YAML configuration file (notably dataset_name_or_id) and from CLI/kwargs arguments are concatenated into a command string without quoting or validation and then…

more

passed to subprocess with shell=True, so shell metacharacters (e.g., ';' on Linux, '&' on Windows) are interpreted. If a victim loads and processes a crafted configuration file — for example by instantiating nnUNetV2Runner with the malicious YAML and invoking a training/validation job such as train_single_model() — arbitrary commands are executed with the privileges of the user running the job.

CWE(s)

Related Threats

MITRE ATT&CK Enterprise Techniques

T1059 Command and Scripting Interpreter Execution
Adversaries may abuse command and script interpreters to execute commands, scripts, or binaries.
T1059.001 PowerShell Execution
Adversaries may abuse PowerShell commands and scripts for execution.
T1059.003 Windows Command Shell Execution
Adversaries may abuse the Windows command shell for execution.
T1059.004 Unix Shell Execution
Adversaries may abuse Unix shell commands and scripts for execution.
T1190 Exploit Public-Facing Application Initial Access
Adversaries may attempt to exploit a weakness in an Internet-facing host or system to initially access a network.
Derived from this CVE’s CWE(s) via the direct CWE→ATT&CK cross-walk.

CVEs Like This One

CVE-2026-45630Shared CWE-78
CVE-2025-24385Shared CWE-78
CVE-2024-39935Shared CWE-78
CVE-2026-81349Shared CWE-78
CVE-2024-8190Shared CWE-78
CVE-2025-48501Shared CWE-78
CVE-2025-23344Shared CWE-78
CVE-2024-20720Shared CWE-78
CVE-2026-71923Shared CWE-78
CVE-2026-48165Shared CWE-78

Affected Assets

project-monai
monai
≤ 1.6.0

Mitigating Controls

Control response

Prevent
Stop it (NIST 800-53)

—

Detect
Catch it (NIST detect / respond)

—

Harden
Shrink the surface (DISA STIG)

—

Validate
Prove the fix (OWASP ASVS)
  • V1.2.5
  • V1.2.8

Mitigating Controls (NIST 800-53 r5) AI

Least privilege reduces the permissions available to any process that could be subverted by injected commands.

Least functionality restricts available OS commands and interpreters, limiting the blast radius of injection.

Developer testing and evaluation can discover missing or incorrect command sanitization during development.

Secure engineering principles require proper neutralization of untrusted input before command construction.

Input validation directly neutralizes or rejects special characters that would otherwise alter OS command structure.

Mitigating Controls (NIST CSF 2.0) AI

Derived directly from the weakness types (CWEs) cited in the NVD entry via our AI-authored CWE→CSF cross-walk (authority under review) — links open the control.

PR.PS-06 mostly match
prevents

PR.PS-06's SDLC practices directly require secure coding and input handling that blocks command-injection defects, yet the single broad outcome leaves many specific neutralization vectors and verification gaps unaddressed.

PR.PS-02 partial match
prevents

Routine patching/maintenance can remediate known command-injection CVEs in dependencies (partial forward) but does nothing to stop developers from introducing improper neutralization in custom code (none reverse).

Mitigating Controls (ISO/IEC 27001:2022 Annex A) AI

Derived directly from the weakness types (CWEs) cited in the NVD entry via our AI-authored CWE→ISO cross-walk (authority under review) — links open the control.

removes
removes
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removes

References