Security Resilience

CVE-2023-1966

Illumina Nextseq 550Dx Firmware 1.0.0 – 1.3.1

Published
28 April 2023
Modified
21 November 2024
Patch / advisory
CVSS Score v3.1 7.4
Click a component to see what it means
Raw vectorCVSS:3.1/AV:P/AC:L/PR:L/UI:N/S:C/C:H/I:H/A:H
EPSS Score 0.0092 59th percentile
Risk Priority 54 floored blend · peak EPSS

CVSS and EPSS are reproduced from their sources (NVD, FIRST EPSS). Risk Priority is our own derived reading, not an NVD score.

Summary

CVE-2023-1966 is a high-severity Execution with Unnecessary Privileges (CWE-250) vulnerability in Illumina Nextseq 550Dx Firmware. Its CVSS base score is 7.4 (High).

Operationally, exploitation aligns with the MITRE ATT&CK technique Data Obfuscation (T1001); ranked in the top 41% of CVEs by exploit likelihood; it is not currently listed in the CISA KEV catalog.

OWASP Top 10 for Web (2025)

EU & UK References

Vulnerability Data

Instruments with Illumina Universal Copy Service v1.x and v2.x contain an unnecessary privileges vulnerability. An unauthenticated malicious actor could upload and execute code remotely at the operating system level, which could allow an attacker to change settings, configurations, software, or…

more

access sensitive data on the affected product.

CWE(s)

Related Threats

MITRE ATT&CK Enterprise Techniques

T1001 Data Obfuscation Command And Control
Adversaries may obfuscate command and control traffic to make it more difficult to detect.
T1001.001 Junk Data Command And Control
Adversaries may add junk data to protocols used for command and control to make detection more difficult.
T1007 System Service Discovery Discovery
Adversaries may try to gather information about registered local system services.
T1011 Exfiltration Over Other Network Medium Exfiltration
Adversaries may attempt to exfiltrate data over a different network medium than the command and control channel.
T1027.003 Steganography Stealth
Adversaries may use steganography techniques in order to prevent the detection of hidden information.
T1027.004 Compile After Delivery Stealth
Adversaries may attempt to make payloads difficult to discover and analyze by delivering files to victims as uncompiled code.
Derived from this CVE’s CWE(s) via the direct CWE→ATT&CK cross-walk.

CVEs Like This One

CVE-2023-1968Same product: Illumina Iscan
CVE-2023-4662Shared CWE-250, CWE-269
CVE-2026-50566Shared CWE-250, CWE-269
CVE-2023-0664Shared CWE-250, CWE-269
CVE-2023-31175Shared CWE-250, CWE-269
CVE-2025-46116Shared CWE-250, CWE-269
CVE-2026-53605Shared CWE-250, CWE-269
CVE-2025-58432Shared CWE-250, CWE-269
CVE-2023-25521Shared CWE-250, CWE-269
CVE-2023-43018Shared CWE-250, CWE-269

Affected Assets

illumina
iscan firmware
4.0.0, 4.0.5
illumina
iseq 100 firmware
all versions
illumina
miniseq firmware
≥ 2.0
illumina
miseq firmware
≥ 4.0
illumina
miseqdx firmware
4.0 · ≥ 4.0.1
illumina
nextseq 500 firmware
4.0
illumina
nextseq 550 firmware
4.0
illumina
nextseq 550dx firmware
4.0 · 1.0.0 — 1.3.1 · ≥ 1.3.3
illumina
nextseq 1000 firmware
1.4.1
illumina
nextseq 2000 firmware
1.4.1
+1 more product configuration(s) — see NVD for full list

Mitigating Controls

Control response

Prevent
Stop it (NIST 800-53)

—

Detect
Catch it (NIST detect / respond)

—

Harden
Shrink the surface (DISA STIG)
  • 4 hardening rules · 4 OS baselines
Validate
Prove the fix (OWASP ASVS)
  • V10.2.3
  • V13.2.2

Likely Mitigating Controls AI

Per-CVE control mapping for this CVE has not run yet; the list below is derived from the weakness types (CWEs) cited in the NVD entry.

addresses: CWE-269 CWE-250

Policy addresses roles, responsibilities, and privilege management to prevent improper privilege assignments.

addresses: CWE-269 CWE-250

Access supervision ensures privileges are assigned and managed without improper escalation or retention.

addresses: CWE-269 CWE-250

Assigning group/role memberships and access authorizations (privileges) while reviewing accounts addresses improper privilege management.

addresses: CWE-250 CWE-269

Separation of duties prevents any single user from holding all privileges needed to complete a critical task, directly reducing execution with unnecessary privileges.

addresses: CWE-250 CWE-269

Directly prevents execution with more privileges than needed for assigned tasks.

addresses: CWE-250 CWE-269

Role-based training on least privilege principles reduces the chance personnel assign or retain unnecessary privileges.

addresses: CWE-250 CWE-269

Analysis of audit records can identify execution with unnecessary privileges through unusual activity patterns.

addresses: CWE-269 CWE-250

Terminating and reviewing connections manages privileges associated with internal interfaces.

Mitigating Controls (NIST CSF 2.0) AI

Derived directly from the weakness types (CWEs) cited in the NVD entry via our AI-authored CWE→CSF cross-walk (authority under review) — links open the control.

PR.AA-05 mostly match
blocks

PR.AA-05 directly enforces least privilege so largely eliminates CWE-250 at design time, yet the weakness can still arise from runtime escalation paths, third-party code, or misapplied role definitions outside this single control.

Mitigating Controls (ISO/IEC 27001:2022 Annex A) AI

Derived directly from the weakness types (CWEs) cited in the NVD entry via our AI-authored CWE→ISO cross-walk (authority under review) — links open the control.

removes
blocks

A.5.15's policy, requirements, and rules for determining/minimizing access rights (incl. privileged access restrictions, need-to-know, least-privilege-like mapping, and role-based consistency) directly stop most unnecessary-privilege execution by design; bounded remainder is runtime elevation or misconfigured enforcement that still requires other controls (e.g. 8.2, 8.3) to act.

removes
blocks

Requiring explicit justification and time-limited grants discourages the routine allocation of unnecessary privileges that would otherwise allow execution with more rights than required.

blocks

Defining and communicating authorization levels for each role limits the assignment of excessive or unnecessary privileges.

Hardening callouts derived

Configuration rules from DISA STIG baselines that bear on weaknesses of the type cited by this CVE. Each rule is shown with the relationship its mapping actually records, against the CWE it was authored against. Derived via CVE→CWE over `controls_xwalks` (higher-evidence rows only; rows rated `none` are excluded).

Windows 10 (1 rule)
  • V-220712 Only accounts responsible for the administration of a system must have Administrator rights on the system. blocks CWE-250
Windows Server 2016 (1 rule)
  • V-225007 Only administrators responsible for the member server or standalone or nondomain-joined system must have Administrator rights on the system. blocks CWE-250
Windows Server 2019 (1 rule)
  • V-205746 Windows Server 2019 must only allow Administrators responsible for the member server or standalone or nondomain-joined system to have Administrator rights on the system. blocks CWE-250

References