Raw vector
CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:HCVSS and EPSS are reproduced from their sources (NVD, FIRST EPSS). Risk Priority is our own derived reading, not an NVD score.
Summary
CVE-2025-54304 is a critical-severity Exposure of Sensitive Information to an Unauthorized Actor (CWE-200) vulnerability in Thermofisher Ion Torrent Onetouch 2 Firmware. Its CVSS base score is 9.8 (Critical).
Operationally, exploitation aligns with the MITRE ATT&CK technique Token Impersonation/Theft (T1134.001); ranked at the 40th percentile by exploit likelihood (below the median); it is not currently listed in the CISA KEV catalog.
The strongest mitigations our analysis identified map to AC-3 (Access Enforcement) and AC-4 (Information Flow Enforcement) — see the control section below for these in your framework.
Deeper analysis AI-assisted summary
Synthesised by an AI model from the NVD description and linked references — a reading aid, not an authoritative source.
CVE-2025-54304 is a high-severity vulnerability (CVSS 3.1 score of 9.8) affecting Thermo Fisher Ion Torrent OneTouch 2 devices with part number INS1005527. The issue stems from an X11 display server that starts automatically when the device is powered on, listening on all network interfaces over TCP port 6000. By default, the X11 access control list permits connections only from 127.0.0.1 and 192.168.2.15. However, if the device is later connected to a network using DHCP and assigned a different IP address, the display server becomes accessible to other devices on the network, exposing sensitive information (CWE-200).
Any unauthenticated attacker with network access to the device can exploit this vulnerability with low complexity, requiring no privileges or user interaction. By connecting to the exposed X11 server on port 6000, an attacker can interact with the matchbox-desktop environment to spawn a terminal, achieving remote code execution with root privileges. This grants high confidentiality, integrity, and availability impacts, potentially allowing full device compromise.
No patches or mitigations are available, as the vulnerability affects products no longer supported by the maintainer. References point to Thermo Fisher user guides and product documentation, which describe system setup but do not address this issue or provide remediation steps. Security practitioners should isolate these legacy devices on segmented networks or air-gapped environments to prevent exposure.
OWASP Top 10 for Web (2025)
EU & UK References
- 🇪🇺 ENISA EUVD: EUVD-2025-201179
Vulnerability Data
An issue was discovered on Thermo Fisher Ion Torrent OneTouch 2 INS1005527 devices. When they are powered on, an X11 display server is started. The display server listens on all network interfaces and is accessible over port 6000. The X11…
more
access control list, by default, allows connections from 127.0.0.1 and 192.168.2.15. If a device is powered on and later connected to a network with DHCP, the device may not be assigned the 192.168.2.15 IP address, leaving the display server accessible by other devices on the network. The exposed X11 display server can then be used to gain root privileges and the ability to execute code remotely by interacting with matchbox-desktop and spawning a terminal. NOTE: This vulnerability only affects products that are no longer supported by the maintainer.
- CWE(s)
Related Threats
MITRE ATT&CK Enterprise Techniques
CVEs Like This One
Affected Assets
Mitigating Controls
Control response
—
—
- 6 hardening rules · 5 OS baselines
V10.4.9V11.7.1V14.1.2V14.2.4
Mitigating Controls (NIST 800-53 r5) AI
Access enforcement directly stops unauthorized actors from obtaining sensitive information.
Information flow enforcement structurally prevents sensitive data from reaching unauthorized recipients.
Protection of information at rest prevents unauthorized exposure of stored sensitive data.
Transmission confidentiality mechanisms stop exposure of sensitive data on the wire.
Least privilege reduces the set of actors who can reach sensitive information.
Mitigating Controls (NIST CSF 2.0) AI
Derived directly from the weakness types (CWEs) cited in the NVD entry via our AI-authored CWE→CSF cross-walk (authority under review) — links open the control.
PR.AA-05 directly enforces least-privilege authorization that blocks most unauthorized disclosures, yet CWE-200 also arises from logging, error messages, and side-channel paths that access controls alone do not address.
PR.DS-10 mostly prevents CWE-200 by directly eliminating unauthorized access to sensitive data-in-use, yet only partially addresses the weakness because CWE-200 spans many other exposure vectors outside runtime protection.
PR.IR-01's segmentation/zero-trust controls largely eliminate network-level unauthorized access paths that enable exposure, yet CWE-200 spans many additional vectors (API responses, logs, app logic) that network controls alone cannot close.
Secure SDLC practices catch most exposure flaws via design, testing and release controls, yet CWE-200 spans runtime/config issues a single development outcome cannot fully close.
PR.AA-01 supplies proper credential lifecycle controls that reduce unauthorized access paths, yet leaves many other exposure vectors (error messages, logging, side channels, etc.) unaddressed.
Authentication verifies actor identity and is a prerequisite for access decisions, yet addresses only one facet of the broad set of exposure vectors in CWE-200.
Mitigating Controls (ISO/IEC 27001:2022 Annex A) AI
Derived directly from the weakness types (CWEs) cited in the NVD entry via our AI-authored CWE→ISO cross-walk (authority under review) — links open the control.
Restricting anonymous or unknown access and encrypting high-value information limits the exposure of sensitive data that would otherwise be obtainable by unauthorized actors.
Suppressing system details, error specifics, and previous log-on information until successful authentication reduces the information an unauthenticated attacker can gather.
By requiring owners to assign sensitivity labels and corresponding handling rules, the control ensures that information is not left unmarked and therefore reduces the chance that sensitive data will be exposed to unauthorized actors.
Requiring encryption, access controls, and recipient authentication for transfers directly reduces the chance that sensitive data reaches an unauthorized observer.
Secure delivery, protected storage, and confidentiality of allocation records limit exposure of authentication material to unauthorized observers.
Requiring defined procedures, assigned roles, and technical/organizational measures for handling PII reduces the chance that sensitive personal data will be exposed to unauthorized actors through inadequate handling or missing safeguards.
Hardening callouts derived
Configuration rules from DISA STIG baselines that bear on weaknesses of the type cited by this CVE. Each rule is shown with the relationship its mapping actually records, against the CWE it was authored against. Derived via CVE→CWE over `controls_xwalks` (authoritative rows only; rows rated `none` are excluded).
Ubuntu 22.04 (1 rule)
- V-260470 Ubuntu 22.04 LTS, when booted, must require authentication upon booting into single-user and maintenance modes. prevents CWE-200
Ubuntu 24.04 (2 rules)
- V-270647 Ubuntu 24.04 LTS must not have the telnet package installed. prevents CWE-200
- V-270675 Ubuntu 24.04 LTS when booted must require authentication upon booting into single-user and maintenance modes. prevents CWE-200
Windows 10 (1 rule)
- V-220737 Administrative accounts must not be used with applications that access the Internet, such as web browsers, or with potential Internet sources, such as email. prevents CWE-200
Windows Server 2016 (1 rule)
- V-224974 Domain-created Active Directory Organizational Unit (OU) objects must have proper access control permissions. prevents CWE-200
Windows Server 2019 (1 rule)
- V-205743 Windows Server 2019 organization created Active Directory Organizational Unit (OU) objects must have proper access control permissions. prevents CWE-200