Cyber Resilience

CVE-2021-38646

HighCISA KEVActive ExploitationEUVD ExploitedRansomware-linked

Published: 15 September 2021

Published
15 September 2021
Modified
30 October 2025
KEV Added
28 March 2022
Patch
CVSS Score v3.1 7.8 CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H
EPSS Score 0.5093 97.9th percentile
Risk Priority 66 60% EPSS · 20% KEV · 20% CVSS

Summary

CVE-2021-38646 is a high-severity an unspecified weakness vulnerability in Microsoft Office. Its CVSS base score is 7.8 (High).

Operationally, ranked in the top 2.1% of CVEs by exploit likelihood; CISA has added it to the Known Exploited Vulnerabilities catalog.

The strongest mitigations our analysis identified are NIST 800-53 SI-2 (Flaw Remediation) and CM-7 (Least Functionality).

Deeper analysis

The vulnerability is a remote code execution flaw in the Microsoft Office Access Connectivity Engine, assigned CVE-2021-38646 with a CVSS 3.1 base score of 7.8. It affects the Access Connectivity Engine component within Microsoft Office installations.

An unauthenticated local attacker can trigger the issue by convincing a user to open a specially crafted file, resulting in arbitrary code execution with high impact to confidentiality, integrity, and availability on the affected system.

Microsoft's security advisory provides official guidance on available patches and mitigations for the vulnerability. The issue is also tracked in CISA's catalog of known exploited vulnerabilities, confirming observed real-world exploitation activity.

EU & UK References

Vulnerability details

Microsoft Office Access Connectivity Engine Remote Code Execution Vulnerability

CWE(s)
KEV Date Added
28 March 2022

Related Threats

No named actor attribution yet. ATT&CK technique mapping in progress for this CVE.

Affected Assets

microsoft
365 apps
all versions
microsoft
office
2013, 2016, 2019

Mitigating Controls

Mitigating Controls (NIST 800-53 r5) AI

prevent

Directly requires timely installation of vendor patches for the Access Connectivity Engine flaw, which is the primary mitigation listed in the Microsoft advisory and CISA KEV entry.

preventdetect

Malicious-code protection mechanisms can inspect and block specially crafted Office files before the Access Connectivity Engine processes them.

prevent

Least-functionality configuration can disable or restrict the Access Connectivity Engine component when it is not required, reducing the attack surface for crafted-file RCE.

References