Cyber Resilience

CVE-2025-10996

Memory Safety in Openbabel Open Babel ≤ 3.1.1

Public PoCMemory Safety
Published
26 September 2025
Modified
29 April 2026
CVSS Score v4 1.9
Click a component to see what it means
Raw vectorCVSS:4.0/AV:L/AC:L/AT:N/PR:L/UI:N/VC:L/VI:L/VA:L/SC:N/SI:N/SA:N/E:P/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X
EPSS Score 0.0026 17th percentile
Risk Priority 15 floored blend · peak EPSS

Summary

CVE-2025-10996 is a low-severity Improper Restriction of Operations within the Bounds of a Memory Buffer (CWE-119) vulnerability in Openbabel Open Babel. Its CVSS base score is 1.9 (Low).

Operationally, ranked at the 17th percentile by exploit likelihood (below the median); it is not currently listed in the CISA KEV catalog; a public proof-of-concept is referenced.

The strongest mitigations our analysis identified map to SI-10 (Information Input Validation) and SI-2 (Flaw Remediation) — see the control section below for these in your framework.

EU & UK References

Vulnerability Data

A vulnerability was detected in Open Babel up to 3.1.1. This issue affects the function OBSmilesParser::ParseSmiles of the file /src/formats/smilesformat.cpp. Performing manipulation results in heap-based buffer overflow. The attack needs to be approached locally. The exploit is now public and…

more

may be used.

CWE(s)

Related Threats

CVEs Like This One

CVE-2025-10997Same product: Openbabel Open Babel
CVE-2025-10995Same product: Openbabel Open Babel
CVE-2026-2705Same product: Openbabel Open Babel
CVE-2025-10994Same product: Openbabel Open Babel
CVE-2026-2704Same product: Openbabel Open Babel
CVE-2026-4391Shared CWE-119, CWE-122
CVE-2025-11275Shared CWE-119, CWE-122
CVE-2026-5235Shared CWE-119, CWE-122
CVE-2025-3791Shared CWE-119, CWE-122
CVE-2025-2592Shared CWE-119, CWE-122

Affected Assets

openbabel
open babel
≤ 3.1.1

Mitigating Controls

Control response

Prevent
Stop it (NIST 800-53)
  • SI-10 Information Input Validation
  • SI-16 Memory Protection
  • SI-2 Flaw Remediation
Detect
Catch it (NIST detect / respond)

Harden
Shrink the surface (DISA STIG)

Validate
Prove the fix (OWASP ASVS)
  • V17.3.2
  • V1.4.1

Mitigating Controls (NIST 800-53 r5) AI

prevent

Directly requires validation of untrusted SMILES input to the ParseSmiles parser, blocking the malformed data that triggers the heap buffer overflow.

prevent

Enforces memory-protection mechanisms (ASLR, NX, guard pages) that raise the bar for successful exploitation of the CWE-122 heap overflow even if input validation fails.

prevent

Mandates timely patching or replacement of the vulnerable Open Babel 3.1.1 binary containing the known flaw in smilesformat.cpp.

Mitigating Controls (NIST CSF 2.0) AI

Derived directly from the weakness types (CWEs) cited in the NVD entry via our AI-authored CWE→CSF cross-walk (authority under review) — links open the control.

PR.PS-06 full match
prevents

Secure-development practices directly require bounds checking and safe memory handling that prevent heap overflows.

ID.RA-01 partial match
prevents

Vulnerability scanning and code analysis directly surface buffer-boundary flaws.

ID.RA-08 partial match
prevents

Receiving and triaging vulnerability disclosures commonly includes buffer-related reports.

PR.AT-02 partial match
prevents

Developer training on secure coding reduces introduction of memory-buffer errors.

PR.PS-02 partial match
prevents

Patching replaces vulnerable code containing buffer-boundary defects.

Mitigating Controls (ISO/IEC 27001:2022 Annex A) AI

Derived directly from the weakness types (CWEs) cited in the NVD entry via our AI-authored CWE→ISO cross-walk (authority under review) — links open the control.

detects

Security testing in development catches out-of-bounds accesses before release, covering most instances of the weakness.

prevents

Secure development lifecycle mandates memory-safety practices that directly prevent buffer-boundary violations.

prevents

Application security requirements can specify memory-safety rules, but do not prescribe implementation details.

prevents

Secure architecture and engineering principles include memory-safe design patterns that mitigate buffer overflows.

prevents

Secure coding standards explicitly forbid unsafe buffer operations, directly eliminating CWE-119.

none

Change management ensures controlled deployment of fixes for discovered heap-overflow vulnerabilities.

References